25982 Pala. Ste 110.

Mission Viejo, CA 92691

(949) 647 - 4774

25982 Pala. Ste 110.

Mission Viejo, CA 92691

(949) 647 - 4774

Understanding Bone Density Medication(Bisphosphonates)

Understanding Bone Density Medication (Bisphosphonates) and Potential Side Effects in Oral Surgery


Maintaining optimal bone health is crucial for overall well-being, especially when it comes to oral health. However, some individuals may experience a decline in bone density, leading to conditions like osteoporosis or osteopenia. In such cases, healthcare professionals may prescribe bone density medications, commonly known as bisphosphonates, to help strengthen the bones. While these medications offer significant benefits, it is essential to be aware of potential side effects, particularly in the context of oral surgery. In this blog, we will explore the use of bisphosphonates, their benefits, and the associated risks when undergoing oral surgical procedures.

Understanding Bisphosphonates:

Bisphosphonates are a class of drugs that work by slowing down the rate of bone loss, thereby increasing bone density and reducing the risk of fractures. They are commonly prescribed to individuals with conditions such as osteoporosis or those undergoing cancer treatments that may weaken the bones. Bisphosphonates inhibit the activity of cells called osteoclasts, responsible for breaking down and resorbing bone tissue.

Oral Surgery and Potential Side Effects:

While bisphosphonates can effectively strengthen bones, they have been associated with a rare but serious side effect known as medication-related osteonecrosis of the jaw (MRONJ) or bisphosphonate-related osteonecrosis of the jaw (BRONJ). MRONJ is characterized by the death of bone tissue in the jaw, leading to exposed bone and potential infection. This condition primarily affects the jawbone and may occur spontaneously or following dental procedures, such as tooth extractions or dental implants.

Risk Factors and Precautions:

It is important to note that the risk of developing MRONJ is relatively low, especially when considering the significant benefits of bisphosphonates in managing bone density disorders. However, certain risk factors may increase the likelihood of developing this condition. These factors include high doses and prolonged use of bisphosphonates, invasive dental procedures, poor oral hygiene, the presence of gum disease, and the use of other medications like corticosteroids.

To minimize the risk of MRONJ, a collaborative approach between patients, dentists, and prescribing physicians is crucial. Communication is key, and patients should inform their dental professionals about their bisphosphonate use, dosage, and duration. Dentists may consider modifying treatment plans, such as avoiding invasive procedures or adjusting medication dosages before surgery. Additionally, maintaining good oral hygiene practices, including regular dental check-ups and thorough cleaning, is essential for reducing the risk of complications.


Bone density medications, such as bisphosphonates, play a vital role in managing conditions like osteoporosis and osteopenia. While these medications provide significant benefits, it is important to be aware of potential side effects, particularly in the context of oral surgery. MRONJ is a rare but serious condition associated with bisphosphonate use, primarily affecting the jawbone. By proactively communicating with healthcare providers and adopting precautionary measures, the risk of developing MRONJ can be minimized. As with any medical treatment, it is essential to weigh the benefits against the potential risks and make informed decisions in consultation with healthcare professionals.

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